Alignment of alleles: Channel catfish (Ictalurus punctatus) IGHV12S2

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

                                  1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                 S   V   E   F   I   Q   S   D   K       I   V   V   R   A   G   E   A   F   T
  AY238373,IGHV12S2*01          TCG GTT GAA TTT ATT CAG TCA GAT AAA ... ATA GTT GTA CGA GCT GGG GAG GCA TTT ACC

                                                        _________________CDR1-IMGT______________________
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                 I   S   C   K   F   S   G   F   S   I   S   S   Y   C                   P   R
  AY238373,IGHV12S2*01          ATC TCC TGT AAA TTC TCT GGG TTT TCA ATA TCC AGC TAC TGT ... ... ... ... CCT CGC

                                                                                            _____________CDR2-IM
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                 W   I   R   Q   M   P   S   K   T   L   E   Y   I   G   Y   V   C   G   S   S
  AY238373,IGHV12S2*01          TGG ATT CGA CAA ATG CCA TCC AAG ACT TTG GAA TAT ATT GGA TAT GTG TGT GGC AGC AGC

                                GT__________________
                                 61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                 S                   N   V   K   D   S   L   K       S   K   M   S   F   S   A
  AY238373,IGHV12S2*01          TCT ... ... ... ... AAT GTA AAG GAC TCA CTC AAG ... AGT AAA ATG AGT TTC TCT GCA

                                 81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                 D   V   S   S   S   T   V   F   L   K   G   Q   N   F   Q   T   E   D   T   A
  AY238373,IGHV12S2*01          GAT GTC TCC AGC AGC ACA GTG TTT TTA AAG GGG CAA AAT TTT CAG ACG GAG GAC ACA GCT

                                                _CDR3-IMGT_
                                101 102 103 104 105 106 107
                                 V   Y   Y   C   A   R   H
  AY238373,IGHV12S2*01          GTG TAT TAC TGC GCA CGA CAT #c
#c: rearranged cDNA

This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001)

Created: 06/11/2003
Author: Nathalie Bosc